Thursday, May 15, 2014
Salbutamol, Ventolin, Ventolin Rotocaps, Volmax
Action:
Synthetic sympathomimetic amine and moderately selective beta2-adrenergic agonist with comparatively long action. Acts more prominently on beta2 receptors (particularly smooth muscles of bronchi, uterus, and vascular supply to skeletal muscles) than on beta1 (heart) receptors. Minimal or no effect on alpha-adrenergic receptors. Inhibits histamine release by mast cells.
Classifications:
autonomic nervous system agent; beta-adrenergic agonist (sympathomimetic); bronchodilator (respiratory smooth muscle relaxant)
Indication:
To relieve bronchospasm associated with acute or chronic asthma, bronchitis, or other reversible obstructive airway diseases. Also used to prevent exercise-induced bronchospasm.
TABLE
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Drug Name
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Dosage & Route
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Action
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Indication
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Adverse Effects
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Contraindication
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Nursing Responsibility
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ALBUTEROL
(al-byoo'ter-ole)) Accuneb, Novosalmol  , Proventil,
Proventil HFA, Proventil Repetabs, Salbutamol, Ventolin, Ventolin Rotocaps,
Volmax
Classifications: autonomic nervous system agent; beta-adrenergic agonist
(sympathomimetic); bronchodilator
(respiratory smooth muscle relaxant)
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Bronchospasm
Adult: PO 2–4 mg 3–4 times/d, 4–8 mg sustained release 2 times/d Inhaled 1–2 inhalations q4–6h Child: PO 2–6 y, 0.1–0.2 mg/kg t.i.d. (max: 4 mg/dose); 6–12 y, 2 mg 3–4 times/d; Inhaled 6–12 y, 1–2 inhalations q4–6h |
Synthetic sympathomimetic amine and moderately selective
beta2-adrenergic agonist with comparatively long action. Acts more
prominently on beta2 receptors (particularly smooth muscles of
bronchi, uterus, and vascular supply to skeletal muscles) than on beta1
(heart) receptors. Minimal or no effect on alpha-adrenergic receptors.
Inhibits histamine release by mast cells.
|
To relieve bronchospasm associated with acute or chronic asthma, bronchitis, or other reversible obstructive airway diseases. Also used to prevent exercise-induced bronchospasm. |
Body as a
Whole: Hypersensitivity reaction. CNS: Tremor, anxiety, nervousness, restlessness,
convulsions, weakness, headache, hallucinations. CV: Palpitation, hypertension,
hypotension, bradycardia, reflex tachycardia. Special
Senses: Blurred vision, dilated pupils. GI: Nausea, vomiting. Other: Muscle cramps, hoarseness.
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Pregnancy (category C), lactation. Use of oral syrup in
children <2 y.
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