Thursday, May 15, 2014
Action:
Vitamin B complex essential for nucleoprotein synthesis and maintenance of normal erythropoiesis. Acts against folic acid deficiency that impairs thymidylate synthesis and results in production of defective DNA that leads to megaloblast formation and arrest of bone marrow maturation.
Classification:
Vitamin B9
Indication:
Folate deficiency, macrocytic anemia, and megaloblastic anemias associated with malabsorption syndromes, alcoholism, primary liver disease, inadequate dietary intake, pregnancy, infancy, and childhood.
TABLE
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Drug Name
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Dosage & Route
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Action
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Indication
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Adverse Effects
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Contraindication
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Nursing Responsibility
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FOLIC ACID (VITAMIN B9, PTEROYLGLUTAMIC ACID)
(fol'ic)
Classifications
Vitamin B9
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Therapeutic
Adult: PO/IM/SC/IV  1 mg/dChild: PO/IM/SC/IV 1 mg/dMaintenance Adult: PO/IM/SC/IV 0.4 mg/dChild: PO/IM/SC/IV <4 y, 0.3 mg/d; >4 y, 0.4 mg/dInfant: PO/IM/SC/IV 0.1 mg/d |
Vitamin B complex essential for nucleoprotein synthesis
and maintenance of normal erythropoiesis. Acts against folic acid deficiency
that impairs thymidylate synthesis and results in production of defective DNA
that leads to megaloblast formation and arrest of bone marrow maturation.
|
Folate deficiency, macrocytic anemia, and megaloblastic
anemias associated with malabsorption syndromes, alcoholism, primary liver
disease, inadequate dietary intake, pregnancy, infancy, and childhood.
|
Reportedly nontoxic. Slight flushing and feeling of warmth
following IV administration.
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Folic acidalone for pernicious anemia or other vitamin B12
deficiency states; normocytic, refractory, aplastic, or undiagnosed anemia.
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Assessment & Drug Effects
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